Protein abundance in ischemic failing versus non-failing human hearts

Archived study

Compares protein abundance in 12 ischemic failing and 10 non-failing male hearts using PXD021261. Two of 1,327 protein groups—TF and a CP-associated group—met 5% FDR on the archived MaxLFQ scale, but neither did after sample-median centering.

Interpretation and limits

The small-sample findings are normalization-sensitive, not a general heart-failure signature. CP protein-group identity remains unresolved, and verified batch mapping was unavailable. The study does not establish diagnostic or causal effects.

Package and provenance

The unchanged research package comes from upstream Case 8. It includes the archived session, analysis materials, results and figures. The poster uses an AI-generated illustrative photograph. This introduction summarizes archived findings; the analysis was not rerun.

Import provenance

This case was added to the Academic Research category on 2026-10-13, with the archived upstream case recorded as its source. The supplied session export and poster were uploaded without changing their contents. This introduction summarizes the archived findings and was standardized for the repository. The study, external data sources, and scientific results were not rerun or independently reverified for this import.

This GitHub catalog imports the case from the verified Hugging Face snapshot. The session export is referenced through that fixed revision; the cover and introduction are stored in this repository.

Case files

• Session export
• Case poster