RAS mutations in two public pancreatic cohorts

Archived study

Compares reported RAS mutations in two public pancreatic cohorts under an explicit ductal-histology rule. KRAS mutations occurred in 104/150 TCGA patients (69.3%) and 130/135 CPTAC patients (96.3%), a descriptive difference of 27.0 percentage points.

Interpretation and limits

Cohorts differ in stage, assays, cellularity and metadata; donor independence is not established. Unprofiled patients remain unknown, not mutation-negative. These results are neither population prevalence estimates nor a causal explanation of the difference.

Package and provenance

The unchanged research package comes from upstream Case 18. It includes the archived session, analysis materials, results and figures. The poster uses an AI-generated illustrative photograph. This introduction summarizes archived findings; the analysis was not rerun.

Import provenance

This case was added to the Academic Research category on 2026-10-13, with the archived upstream case recorded as its source. The supplied session export and poster were uploaded without changing their contents. This introduction summarizes the archived findings and was standardized for the repository. The study, external data sources, and scientific results were not rerun or independently reverified for this import.

This GitHub catalog imports the case from the verified Hugging Face snapshot. The session export is referenced through that fixed revision; the cover and introduction are stored in this repository.

Case files

• Session export
• Case poster